Police on Saturday detained the manager of the Green Cozy Cottage building in connection with the fire in the capital’s Bailey Road area.
Hamimul Haque Bipul, the manager of the building owner, was detained from Dhanmondi.
Earlier, three others -- Anwarul Haque and Shafiqur Rahman Rimon, owners of Chumuk restaurant, and Md Jisan, manager of Kacchi Bhai restaurant were detained.
Additional Commissioner of DMP Dr Kh Mahid Uddin confirmed the incident. A case was filed by police on Friday night.
At least 46 people were killed, and over 20 others sustained severe injuries by a devastating fire on Thursday night.
Firefighters rescued 70 people, including 42 in unconscious state, from the rooftop and different floors of the seven-storey Green Cozy Cottage.
The fire broke out at around 9:45pm.
Most of the people died as they jumped off the building or from burns or suffocation, said firefighters who brought the fire under control around 12:30am.
Fire officials say the blaze spread fast due to the presence of gas cylinders on several floors in the restaurant kitchens. People could not leave the building due to smoke in the staircase.