A significant proportion of young diabetes patients in Bangladesh have been found to be affected by Maturity Onset Diabetes of the Young (MODY), a distinct form of diabetes, according to a new study conducted by Bangladesh Medical University (BMU).
The study revealed that nearly one in every five suspected young diabetes patients showed genetic variations associated with MODY.
The findings were presented at a programme titled “Dissemination of Published PhD Research of Dr Mashfiqul Hasan,” held on Thursday at the Shaheed Dr Milon Hall of BMU.
Researchers reported that specific genetic alterations linked to MODY were identified among young diabetes patients. These variations were found predominantly in less commonly studied genes, which differ from patterns typically observed in Western populations. They also noted that clinically distinguishing between patients with and without these genetic variations remains challenging.
The researchers cautioned that the study is preliminary and exploratory in nature, and emphasized the need for larger-scale research before applying the findings in clinical practice.
The researchers also highlighted that this form of diabetes is neither new nor the same as Type 1 or Type 2 diabetes.
They further explained that MODY is a separate form of diabetes that is neither Type 1 nor Type 2, underscoring the importance of accurate diagnosis through genetic testing to ensure appropriate treatment.
Therefore, identifying MODY cases through proper diagnosis and genetic research is essential to ensure accurate treatment.
The event also noted that diabetes prevalence among young people in Bangladesh is increasing, but many cases do not fit into conventional diabetes classifications. The findings suggest that the genetic pattern of diabetes in Bangladesh may differ from other regions, and existing diagnostic methods may not be fully suitable for the local population.
The research has recently been published in a Q1-ranked international journal, indicating its global scientific relevance.
Vice-Chancellor of BMU Professor Dr FM Siddiqi, the chief guest at the event, said that conducting such genetic studies in Bangladesh is highly complex, but further research is essential for improving diagnosis and ensuring proper treatment for patients.
The session was chaired by Professor Dr MA Hasanat, Chairman of the Department of Endocrinology at BMU. Researchers Dr Mashfiqul Hasan, Professor Dr Indrajit Prasad, and Dr Mohammad Salimullah also addressed the event.
Speakers said the initiative aims to disseminate research findings among doctors, students, and researchers, raise awareness about diabetes among young people, and encourage further research to improve patient care in Bangladesh. They added that in some cases MODY can be managed with little or no medication, making correct identification crucial to avoid inappropriate treatment.