• Monday, Oct 25, 2021
  • Last Update : 02:06 am

Pfizer says Covid jab safe for children aged 5-11

  • Published at 09:04 pm September 20th, 2021
Pfizer_Vaccine_Reuter
A small shopping basket filled with vials labelled 'Covid-19 - Coronavirus Vaccine' and a medical syringe are placed on a Pfizer logo Reuters

The trial results are the first of their kind for children under 12

Pfizer and BioNTech on Monday said trial results showed their coronavirus vaccine was safe and produced a robust immune response in children aged five to 11, adding that they would seek regulatory approval shortly.

The vaccine would be administered at a lower dosage than for people over 12, they said.

"In participants five to 11 years of age, the vaccine was safe, well tolerated and showed robust neutralizing antibody responses," US giant Pfizer and its German partner said in a joint statement.

They plan to submit their data to regulatory bodies in the European Union, the United States and around the world "as soon as possible."

The trial results are the first of their kind for children under 12, with a Moderna trial for six-11-year-olds still ongoing.

Both the Pfizer and Moderna jabs are already being administered to adolescents over 12 and adults in countries around the globe.

Although children are considered less at risk of severe Covid, there are concerns that the highly contagious Delta variant could lead to more serious cases.

Inoculating children is also seen as key to keeping schools open and helping end the pandemic.

"We are eager to extend the protection afforded by the vaccine to this younger population," said Pfizer CEO Albert Bourla, noting that "since July, paediatric cases of Covid-19 have risen by about 240% in the US."

Kids in the 5-11 age trial group received a two-dose regimen of 10 micrograms in the trial, compared with 30 micrograms for older age groups, the companies said. The shots were given 21 days apart.

The 10 micrograms dose was "carefully selected as the preferred dose for safety, tolerability and immunogenicity" for that age group, the statement said.

Under-5s before year-end

The side effects were "generally comparable to those observed in participants 16 to 25 years of age," it added. 

Among the most commonly reported side effects in the past have been pain and swelling at the injection site as well as headache, chills and fever.

Israel has already given special authorisation to vaccinate children aged 5-11 who are "at significant risk of serious illness or death" from Covid, using the Pfizer jab at the lower dosage.

Pfizer and BioNTech are also trialling their vaccine on infants aged six months to two years, and on children aged two to five.

The topline results for those trials are expected "as soon as" the fourth quarter of this year, the companies said.

Altogether, up to 4,500 children aged six months to 11 years have enrolled in the Pfizer-BioNTech trials in the US, Finland, Poland and Spain.

Like its Moderna rival, the Pfizer jab is based on novel mRNA technology that delivers genetic instructions to cells to build the coronavirus spike protein, in order to evoke antibodies when bodies encounter the real virus.

59
Facebook 52
blogger sharing button blogger
buffer sharing button buffer
diaspora sharing button diaspora
digg sharing button digg
douban sharing button douban
email sharing button email
evernote sharing button evernote
flipboard sharing button flipboard
pocket sharing button getpocket
github sharing button github
gmail sharing button gmail
googlebookmarks sharing button googlebookmarks
hackernews sharing button hackernews
instapaper sharing button instapaper
line sharing button line
linkedin sharing button linkedin
livejournal sharing button livejournal
mailru sharing button mailru
medium sharing button medium
meneame sharing button meneame
messenger sharing button messenger
odnoklassniki sharing button odnoklassniki
pinterest sharing button pinterest
print sharing button print
qzone sharing button qzone
reddit sharing button reddit
refind sharing button refind
renren sharing button renren
skype sharing button skype
snapchat sharing button snapchat
surfingbird sharing button surfingbird
telegram sharing button telegram
tumblr sharing button tumblr
twitter sharing button twitter
vk sharing button vk
wechat sharing button wechat
weibo sharing button weibo
whatsapp sharing button whatsapp
wordpress sharing button wordpress
xing sharing button xing
yahoomail sharing button yahoomail