• Wednesday, Oct 28, 2020
  • Last Update : 09:06 pm

Study: Dengue may provide some immunity against Covid-19

  • Published at 08:33 pm September 21st, 2020
mosquito dengue
Bigstock

Places with lower Covid-19 infection rates and slower case growth were locations that had suffered intense dengue outbreaks this year or last

A new study that analyzed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past outbreaks of dengue fever that suggests exposure to the mosquito-transmitted illness may provide some level of immunity against Covid-19.

The not yet published study led by Miguel Nicolelis, a professor at Duke University, and shared exclusively with Reuters, compared the geographic distribution of coronavirus cases with the spread of dengue in 2019 and 2020.

Places with lower coronavirus infection rates and slower case growth were locations that had suffered intense dengue outbreaks this year or last, Nicolelis found.

"This striking finding raises the intriguing possibility of an immunological cross-reactivity between dengue's Flavivirus serotypes and SARS-CoV-2," the study said, referring to dengue virus antibodies and the novel coronavirus.

"If proven correct, this hypothesis could mean that dengue infection or immunization with an efficacious and safe dengue vaccine could produce some level of immunological protection" against the coronavirus, it added.

Nicolelis told Reuters the results are particularly interesting because previous studies have shown that people with dengue antibodies in their blood can test falsely positive for Covid-19 antibodies even if they have never been infected by the coronavirus.

"This indicates that there is an immunological interaction between two viruses that nobody could have expected, because the two viruses are from completely different families," Nicolelis said, adding that further studies are needed to prove the connection.

The study was being published ahead of peer review on the MedRxiv preprint server and will be submitted to a scientific journal.

It highlights a significant correlation between lower incidence, mortality and growth rate of Covid-19 in populations in Brazil where the levels of antibodies to dengue were higher.

Brazil has the world's third highest total of Covid-19 infections with more than 4.4 million cases - behind only the United States and India.

In states such as Paraná, Santa Catarina, Rio Grande do Sul, Mato Grosso do Sul and Minas Gerais, with a high incidence of dengue last year and early this year, Covid-19 took much longer to reach a level of high community transmission compared to states such as Amapá, Maranhão and Pará that had fewer dengue cases.

The team found a similar relationship between dengue outbreaks and a slower spread of Covid-19 in other parts of Latin America, as well as Asia and islands in the Pacific and Indian Oceans.

Nicolelis said his team came across the dengue discovery by accident, during a study focused on how Covid-19 had spread through Brazil, in which they found that highways played a major role in the distribution of cases across the country.

After identifying certain case-free spots on the map, the team went in search of possible explanations. A breakthrough came when the team compared the spread of dengue with that of the coronavirus.

64
62
blogger sharing button blogger
buffer sharing button buffer
diaspora sharing button diaspora
digg sharing button digg
douban sharing button douban
email sharing button email
evernote sharing button evernote
flipboard sharing button flipboard
pocket sharing button getpocket
github sharing button github
gmail sharing button gmail
googlebookmarks sharing button googlebookmarks
hackernews sharing button hackernews
instapaper sharing button instapaper
line sharing button line
linkedin sharing button linkedin
livejournal sharing button livejournal
mailru sharing button mailru
medium sharing button medium
meneame sharing button meneame
messenger sharing button messenger
odnoklassniki sharing button odnoklassniki
pinterest sharing button pinterest
print sharing button print
qzone sharing button qzone
reddit sharing button reddit
refind sharing button refind
renren sharing button renren
skype sharing button skype
snapchat sharing button snapchat
surfingbird sharing button surfingbird
telegram sharing button telegram
tumblr sharing button tumblr
twitter sharing button twitter
vk sharing button vk
wechat sharing button wechat
weibo sharing button weibo
whatsapp sharing button whatsapp
wordpress sharing button wordpress
xing sharing button xing
yahoomail sharing button yahoomail