Defending champions Chelsea closed to within four points of second-place United by beating Watford 4-2 and Tottenham Hotspur can draw level with Mourinho's men if they beat Liverpool on Sunday. United's defeat followed their 0-0 draw at Liverpool last weekend and a laboured 1-0 victory away to Benfica in the Champions League. A furious Mourinho said: "When I lose matches, I like to lose because the opponent was better, had more quality. When you lose because of attitude, that is really bad."
Most goals for Man City (all comps): 177 – Sergio Aguero (262 apps) 177 – Eric Brook (493) 166 – Tommy Johnson (354) 153 – Colin Bell (501) pic.twitter.com/lte4XexRWC— Sky Sports Statto (@SkySportsStatto) October 21, 2017
Huddersfield went ahead five minutes later when Australian Mooy, a former City player, robbed Juan Mata and followed in to score after David de Gea had saved from Tom Ince. Lindelof was at fault as Depoitre added a second in the 33rd minute, his failure to cut out goalkeeper Jonas Lossl's kick allowing Depoitre to round De Gea and score.
A frank assessment of today's result from Ander Herrera... pic.twitter.com/S8ucttuZCw— Manchester United (@ManUtd) October 21, 2017
United substitute Marcus Rashford headed in Romelu Lukaku's cross with 12 minutes remaining, but Huddersfield held firm for a famous win. Pep Guardiola's City have won their last 11 games in all competitions, equalling the club record, and have scored 20 goals in their last four home matches in the league. Argentina striker Aguero netted from the spot on the half hour after Burnley goalkeeper Nick Pope was contentiously adjudged to have fouled Bernardo Silva.
With good leadership, a clear plan and the strongest team there are no limits. What a fight today ?. Definitely one of my proudest wins pic.twitter.com/FKdwYV3oGmOctober 21, 2017
Well, that was fun... pic.twitter.com/3OYy2pxVeo— Premier League (@premierleague) October 21, 2017