Globally, the virus has killed more than 2 million people
The Chinese city of Wuhan marked one year since the start of its traumatic 76-day coronavirus lockdown on Saturday while the pandemic continued to rage elsewhere, with US President Joe Biden warning America's death toll could pass 600,000.
Traffic hummed, sidewalks bustled, and citizens packed parks and public transport in Wuhan, underscoring the scale of the recovery in the metropolis of 11 million where the pathogen first emerged before going global.
The spread of the virus was accelerating elsewhere, with British Prime Minister Boris Johnson saying a new strain that emerged in the UK could be more deadly and more transmissible than the one that menaced Wuhan a year ago.
"In addition to spreading more quickly, it also now appears that there is some evidence that the new variant... may be associated with a higher degree of mortality," Johnson told a news conference.
The sobering news came as Britain reported record deaths from Covid-19, following a surge in cases and hospitalisations since the variant was first identified in southeast England in September.
The nation's death toll -- 95,981 as of Friday -- is the highest in Europe.
In the United States, the world's worst-hit country, the new president gave his highest estimate yet of its eventual toll, as he stepped up federal aid.
"The virus is surging," President Biden told a news conference. "We're at 400,000 dead, expected to reach well over 600,000."
Globally, the virus has killed more than two million people, infected tens of millions of others and hammered economies.
There were new signs of the depth of damage dealt to the global economy, with the closely watched Purchasing Managers' Index showing that Europe was heading for a new recession, while Latin America suffered its steepest drop in foreign trade since the global financial crisis.
In Wuhan, a team of World Health Organization (WHO) experts was still in hotel quarantine ahead of a mission to investigate the source of the virus, and the body said it was too early to conclude whether the pandemic actually started there.
"All hypotheses are on the table," WHO emergencies director Michael Ryan told a press conference in Geneva.
"And it is definitely too early to come to a conclusion of exactly where this virus started, either within or without China."
Beijing is braced for the scrutiny the team will bring to its virus narrative, having drip-fed the idea that the pandemic started outside its borders.
And while Wuhanites looked back on their confinement from the distance of a year, Hong Kong was introducing its first lockdown of the pandemic, the government ordering thousands of residents to stay home as authorities battled an outbreak in one of its poorest and most densely packed districts.
The order bans anyone inside multiple housing blocks within the neighbourhood of Jordan -- about 150 blocks and up to 9,000 people, according to local media -- from leaving their apartment unless they can show a negative test.
Countries across the world were bringing in new measures on Saturday, including the Netherlands, which was set to introduce its first curfew since World War II.
Until February 19, residents will have to stay home from 9pm, local time, until 4:30am, on pain of a $115 fine.
And in the Colombian capital of Bogota, residents were under their third weekend quarantine in a row, meaning the closure of all non-essential shops in the city of eight million from Friday at 8:00pm until Monday at 4:00am.