Wimbledon has banned Russian and Belarusian players from the 2022 tournament in response to the invasion of Ukraine, but ATP and WTA organizers branded the move "unfair" and "very disappointing" Wednesday.
The All England Lawn Tennis Club, which runs Wimbledon, said it was acting to "limit Russia's global influence through the strongest means possible".
Russian men's world No 2 Daniil Medvedev and Belarusian female world No 4 Aryna Sabalenka - a Wimbledon semi-finalist last year - are the leading players affected by the ban.
The Lawn Tennis Association has also banned Russian or Belarusian players from competing in other British grass-court tournaments, including Wimbledon warm-up events at Queen's Club and Eastbourne.
Players from Russia and Belarus have been able to compete on the ATP and WTA tours since the war in Ukraine started, but they were not allowed to use their national flags.
The ITF had already banned both countries' teams from the Davis Cup and the Billie Jean King Cup.
ATP and WTA bosses claim the Wimbledon ban is discriminatory and sets a damaging precedent.
The WTA said the decision was "neither fair nor justified".
Men's world No 1 Novak Djokovic, currently playing in the ATP event in Belgrade, also criticized the decision.
Others hit by the ban are Russia's Andrey Rublev, who is currently eighth in the ATP rankings, while his compatriot Karen Khachanov is in 26th place.
Russian world No 15 Anastasia Pavlyuchenkova and Victoria Azarenka of Belarus are two of the other top female players who will miss the grass-court Grand Slam.
Wimbledon, the most high-profile of tennis's four Grand Slam events, runs from June 27 to July 10 this year.
At present, Russian and Belarusian players are still able to compete at the French Open, which starts in May.
Wimbledon chiefs spoke to the British government earlier in April to discuss whether they should follow a similar policy to the men's and women's circuits.
The AELTC statement added that the ban would be reconsidered if circumstances "change materially" between now and June.
Russia reacted angrily to the reports, deeming it "unacceptable".
The United States Tennis Association acknowledged "the difficult decision made by the All England Club".